Spermicides can lead to miscarrage

Another reason to not use contraception. Thanks to Ladyscott from the Beautiful Womanhood message board for finding this.

Title: Vaginal spermicides and miscarriage seen primarily in the emergency room.
Author: Jick H; Shiota K; Shepard TH; Hunter JR; Stergachis A; Madsen S; Porter JBSource: Teratogenesis, Carcinogenesis, and Mutagenesis. 1982;2(2):205-10.

Abstract: Data are presented on the relation of spermicide use in the frequency and type of miscarriages seen primarily in the emergency room. The study was part of the program of quality assessment of patient care carried out by Group Health Cooperative of Puget Sound (Seattle, Washington). The study population included 5949 women who delivered liveborn children and 222 women who miscarried. Among the 6171 women studies, 813 (13%) had filled a prescription for spermicides within 48 weeks of the estimated date of fertilization: 1127 (18%) had filled a prescription for an oral contraceptive (OC) within 48 weeks of the estimated date of fertilization (EDF); and 4231 (69%) had not filled a prescription for either. Among the 813 spermicide users, 47 (5.8%) had a miscarriage, compared with 35 of 1127 (3.1%) OC users, and 140 of 4231 (3.3%) women who used neither. The risk ratio (RR) estimate comparing spermicide users with all others is 1.8. The RR estimate comparing spermicide users with women who used neither is 1.8. For spermicide users, the rate of miscarriage was 19/255 (75/1000) for women who had filled their last prescription within 12 weeks of the EDF; it was 13/242 (54/1000) for women who filled their last prescription between 13 and 24 weeks prior to the EDF; it was 15/316 (47/1000) for women who filled their last prescription between 25 and 48 weeks prior to the EDF. In all 3 categories the rate was higher than the rate in OC users and the rate in women who use neither. Examination of abortus material revealed that the association with spermicides was strongest among those where an abnormal fetus was present. In the entire series of 222 miscarriages, there were 18 abortuses in which a specific defect(s) was described. The frequency of such events was 4/813 (4.9/1000) for spermicide users, 1/1127 (0.9/1000) for OC users and 13/4231 (3.1/1000) for nonusers. Study results provide additional evidence for the hypothesis that the use of vaginal spermicides near, at, or after the time of conception has a deleterious effect on pregnancy outcome. The data are most consistent with the hypothesis that use must be near or at the time of conception in order for this effect to be present. Language: English Keywords: RETROSPECTIVE STUDIES WASHINGTON SPERMICIDAL CONTRACEPTIVE AGENTS BARRIER METHODS ABORTION, SPONTANEOUS ABORTION INCIDENCE PREGNANCY COMPLICATIONS UNITED STATES COMPLICATIONS Studies Research Methodology North America Americas Developed Countries Contraceptive Agents Contraception Family Planning Contraceptive Methods Diseases Fertility Control, Postconception Measurement Document Number: 010746 Notification http://db.jhuccp.org/ics-...&DF=LongRecordDisplay